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In addition further study is required to evaluate whether id
2019-05-28
In addition, further study is required to evaluate whether identified mutations influence post-translational modifications because they are important mechanism of transcription factors for regulating normal and leukemic hematopoiesis. Authors\' contributions Conflict of interest Acknowledgm
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br Discussion A familial platelet disorder with
2019-05-28
Discussion A familial platelet disorder with a propensity to myeloid malignancy (FPD/MM) was first reported in 1978 and since then approximately 30 pedigrees with RUNX1 germline mutations have been reported in the literature [9,11]. The RUNX1 gene is composed of 10 exons (1–6, 7A, 7B, 7C and 8).
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Fig shows an example of RNRVAS in
2019-05-28
Fig. 3 shows an example of RNRVAS in a dual-chamber pacemaker recipient with sinus node disease, with the pacemaker set in rate adaptive DDI-R mode pacing with an AV interval of 300ms and lower rate limit of 60ppm. The tracing shows sensor-driven DDIR pacing at 80bpm (V–V casein kinase 2 length=750
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Catheter ablation of a concealed right anteroseptal AV
2019-05-28
Catheter ablation of a concealed right anteroseptal AV bypass tract was successfully performed in our patient. Catheter ablation of the anteroseptal accessory pathway did not affect normal AV conduction. The effective refractory period of the fast AV node was 380ms at a pacing ci-1033 length of 700
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PLX 4032 The standard therapy for chordoma is excision Local
2019-05-28
The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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A year old woman presented to our clinic
2019-05-28
A 54-year-old woman presented to our clinic with palpitation and shortness of breath. Six years previously, she underwent successful catheter ablation for focal atrial tachycardia (AT) originating from the EPI-001 cost of the right atrial appendage and right side of the fossa ovalis. However, AT or
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br Materials and methods br
2019-05-28
Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a
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En otro caso la dilatada digresi n
2019-05-28
En otro caso, la dilatada digresión filosófica de tono panteísta culmina en una Mercedes que pronuncia la palabra “cosmos”; el editor, sin duda, transforma este momento climático en una escena con cierta cursilería: Para sorprender al autor al momento de tomar la pluma y enmendarse la página de vez
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In an early meta analysis
2019-05-27
In an early meta-analysis, diagnosing cancer of the pancreas by ERCP with the “double duct” sign had a sensitivity of 92% and specificity of 96%. In the present case, mild proximal CBD dilatation with an abrupt distal CBD stricture was detected by ERCP. The most common malignant cause of obstructive
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br Raising taxes on tobacco is the
2019-05-27
Raising taxes on tobacco is the measure with the “least compliance” worldwide among the set of measures introduced by the WHO to facilitate implementation of its Framework Convention on Tobacco Control programme. In an extended cost-effectiveness analysis, Stéphane Verguet and colleagues (April, 2
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Methods Between and Ridge Regional Hospital adopted
2019-05-27
Methods Between 2013 and 2015, Ridge Regional Hospital adopted a quality improvement programme in three stages. In the first stage, two senior staff members were selected to serve as QI (quality improvement) leaders and received 4 days of training in Six Sigma methods. In the second stage, two front
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The reduction in mother to child transmission MTCT
2019-05-27
The reduction in mother-to-child transmission (MTCT) of HIV is one of the greatest success stories of the antiretroviral therapy (ART) era. However, evidence is accumulating that, despite avoiding HIV, HIV-exposed uninfected (HEU) infants have more infectious morbidity and mortality than HIV-unexpos
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The patient has fared well without any lead malfunctions lea
2019-05-27
The patient has fared well, without any lead malfunctions, lead dislodgement, or inappropriate shocks. Follow-up echocardiography showed no aggravation of tricuspid regurgitation. Sufficiently high atrial and ventricular amplitudes (P-wave: 3.5mV and R-wave: 9.9mV) were confirmed during 18 months of
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There are several limitations to the
2019-05-27
There are several limitations to the procedure described herein. The present GC was developed for engaging the coronary sinus via a right-sided approach. However, this GC was bent dorsally and had the shortest tip and most acute tip angle among the Attain™ family, which facilitated its placement int
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After the success of the Millennium Development
2019-05-24
After the success of the Millennium Development Goals and the reduction in more than 50% of child mortality in children younger than 5 years (Countdown to 2015 report), the survive and thrive motto was given prominence by the Sustainable Development Goals (SDGs). For all children to thrive, we need
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