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          All participants with age years completed the ultramarathon2019-04-29  All participants with age 46.9±9.0 years completed the ultramarathon in 670.0±85.3 minutes. The average distance after 4 hours’ running was 39.3±5.2 km. The average experience in all runners was 5.4±3.4 times, and the average best marathon time was 211.3±21.2 minutes. For the runners in this study, 
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          Bisphosphonates are a well established standard of care trea2019-04-29  Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated 
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          will be remembered as an exceptional2019-04-29  2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi 
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          Definida pelo Estado como crit rio inicial para o andamento2019-04-29  Definida pelo Estado como critério inicial para o andamento das reivindicações quilombolas por reconhecimento e consequentemente Amyloid β-Peptide (1-42) manufacturer políticas públicas e representatividade política, a autoatribuição pode soar simplista se preestabelecermos que os agrupamentos negro 
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          Francisco Panizza ha desarrollado una agenda2019-04-29  Francisco Panizza ha desarrollado una agenda sobre la relación del populismo con la democracia en gran medida gpr55 agonist partir de los trabajos de Laclau. El autor propone atender cuatro dimensiones involucradas en la teoría del populismo: la retórica, la forma de representación, la política y lo 
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          br Prognosis risk stratification Besides age2019-04-29  Prognosis/risk stratification Besides age and performance status, cytogenetic and molecular aberrations are the most important tools to predict outcome in AML [3]. In 2010, the European LeukemiaNet (ELN) classification scheme was created with the aim to standardize risk stratification in adult AM 
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          br Conflict of interest statement2019-04-28  Conflict of interest statement Introduction Bone metastases are exceedingly common among advanced cancer patients, especially in those with breast, prostate, and lung carcinomas [1,2]. They are a cause of great morbidity and result in significant pain in 50–75% of patients at some point throug 
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          AMP activated protein kinase AMPK is2019-04-28  AMP-activated protein kinase (AMPK) is the most important sensor of cellular energy [19,18], and is also activated by hypoxia as a compensatory response to the reduced mitochondrial respiration [20]. The heterotrimeric AMPK composes of two regulatory subunits and one catalytic subunit, which is acti 
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          In addition evidence of similar resting HR s before2019-04-28  In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy 
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          sr9009 Argentina hab a buscado acrecentar las relaciones2019-04-28  Argentina había buscado acrecentar las relaciones con Guatemala desde 1977, coincidentemente con la llegada de Carter sr9009 la presidencia. Estas, sin embargo, avanzaron con el cambio de gobierno en 1978 en Guatemala. Cuando asumió la presidencia Lucas García, el embajador argentino recibió instruc 
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          O paratextos que tambi n2019-04-28  O paratextos que también son performativos en tanto que discursiva mente intervienen en el presente y tienen la intención de modificarlo, como por ejemplo el epígrafe que acompaña E-64 la imagen de la revista Futuro: En este aspecto, el abordaje de la revista en tanto fuente documental ha servido 
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          The overall MSTS score in our study was The MSTS2019-04-28  The overall MSTS score in our study was 97.3%. The MSTS score after curettage treatment was 99%, better than that in previous studies, which ranged from 90% to 93%. Two cohort studies showed higher MSTS scores for patients who underwent intralesional curettage than those who underwent wide resection 
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          br The L type calcium channel LTCC in heart2019-04-28  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot 
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          Since BM impairs the balance between2019-04-28  Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re 
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          br Case report We report on a year old male2019-04-28  Case report We report on a 28-year-old male without any past medical history. After a minor work accident (professional mechanic) he noticed significant pain in his left knee. The pain increased over time and a radiograph was taken. It showed minor bone resorption at the neck of the left proximal 
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