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br Radiotherapy for bone metastases As a palliative interven
2019-04-30
Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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La eleg a de tus ojos Uno
2019-04-30
“La elegía de tus ojos” (1914) Uno de los poemas más tempranos de Pellicer, “La elegía de tus ojos”, ya demuestra un sentido nuevo de historicidad. Escrito en 1914, en el apogeo del posmodernismo y durante la Revolución mexicana, cuando el poeta tenía apenas unos quince años, este poema se adhiere
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What would mitigation strategies to deal with future
2019-04-30
What would mitigation strategies to deal with future pandemic risks of zoonotic disease look like? Analyses of emerging disease trends during the past six decades have shown that Ebola fits the mst2 pattern. This pattern involves zoonotic spillover from wildlife or livestock driven by changes in la
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Este n mero correspondiente al primer semestre del a
2019-04-30
Este número, correspondiente al primer semestre del año 2013, se abre con una sección dedicada am580 reflexionar sobre América Latina desde diferentes puntos cardinales: literatura, ciencia y tecnología, derechos humanos, filosofía, historia de las ideas y dos perspectivas del pensamiento de Francis
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br Introducci n Las encendidas palabras de fray Servando
2019-04-30
Introducción Las encendidas palabras de fray Servando Teresa de Mier provienen del Discurso preliminar que acompaña la reedición de la Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, publicado en México en 1812. Fray Servando no duda en calificar al dominico, l
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Angler a registra la fauna en forma dispersa y fragmentaria
2019-04-30
Anglería registra la URMC-099 en forma dispersa y fragmentaria; sucede casi siempre como una anécdota curiosa de marcado carácter digresivo o cuando el espécimen difiere ostensiblemente de los conocidos o es portador de alguna maravilla; además en su recepción y representación hay resabios del mund
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WHO has recognised the morbidity due to
2019-04-29
WHO has recognised the morbidity due to schistosomiasis in this Rapalink-1 preschool age group and has recommended to treat them on a case by case basis because of the absence of suitable paediatric formulation of praziquantel for inclusion in the preventive chemotherapy. The challenge to ensure th
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All participants with age years completed the ultramarathon
2019-04-29
All participants with age 46.9±9.0 years completed the ultramarathon in 670.0±85.3 minutes. The average distance after 4 hours’ running was 39.3±5.2 km. The average experience in all runners was 5.4±3.4 times, and the average best marathon time was 211.3±21.2 minutes. For the runners in this study,
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Bisphosphonates are a well established standard of care trea
2019-04-29
Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated
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will be remembered as an exceptional
2019-04-29
2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi
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Definida pelo Estado como crit rio inicial para o andamento
2019-04-29
Definida pelo Estado como critério inicial para o andamento das reivindicações quilombolas por reconhecimento e consequentemente Amyloid β-Peptide (1-42) manufacturer políticas públicas e representatividade política, a autoatribuição pode soar simplista se preestabelecermos que os agrupamentos negro
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Francisco Panizza ha desarrollado una agenda
2019-04-29
Francisco Panizza ha desarrollado una agenda sobre la relación del populismo con la democracia en gran medida gpr55 agonist partir de los trabajos de Laclau. El autor propone atender cuatro dimensiones involucradas en la teoría del populismo: la retórica, la forma de representación, la política y lo
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br Prognosis risk stratification Besides age
2019-04-29
Prognosis/risk stratification Besides age and performance status, cytogenetic and molecular aberrations are the most important tools to predict outcome in AML [3]. In 2010, the European LeukemiaNet (ELN) classification scheme was created with the aim to standardize risk stratification in adult AM
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br Conflict of interest statement
2019-04-28
Conflict of interest statement Introduction Bone metastases are exceedingly common among advanced cancer patients, especially in those with breast, prostate, and lung carcinomas [1,2]. They are a cause of great morbidity and result in significant pain in 50–75% of patients at some point throug
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AMP activated protein kinase AMPK is
2019-04-28
AMP-activated protein kinase (AMPK) is the most important sensor of cellular energy [19,18], and is also activated by hypoxia as a compensatory response to the reduced mitochondrial respiration [20]. The heterotrimeric AMPK composes of two regulatory subunits and one catalytic subunit, which is acti
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