• br Methods The Spanish GEM MAS trial lasted

  2019-04-16

  

  Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc

• voltage gated potassium channel TRAF as a multi functional a

  2019-04-16

  

  TRAF6, as a multi-functional adaptor protein, can be rapidly activated following Toll Like Receptor 4 (TLR4) and ligand recognition [39], [40], [41], and plays an important role in inflammatory responses. Increasing evidence implied that TRAF6 is closely related to CNS diseases [42], [43]. In cerebr

• Welcome to the new volume of the the official journal

  2019-04-16

  

  Welcome to the new volume of the , the official journal of the Japanese Heart Rhythm Society (JHRS) and the Asian Pacific Heart Rhythm Society (APHRS). The highlight of the 2013 volume is the publication of 2 . The first special issue is titled “Brugada syndrome from bench to bedside,” edited by gu

• The final variant deals with a

  2019-04-16

  

  The final variant deals with a patient who has a poor prognosis due to visceral metastases and who suffers from a single site of painful bone disease. The purpose of the case was to evaluate the panel\'s views of supportive care with analgesic medications plus or minus EBRT. The group did recommend

• br Benign bone tumors br Giant

  2019-04-16

  

  Benign bone tumors Giant cell tumor of jaws [GCT] GCTs arising in the head and neck region constitute approximately 2% of all GCTs. They are locally aggressive, recurrent and non-metastasing. Neoplastic giant cell are very rare in jaws. GCT usually occurs in children and young adults, predomin

• During the ACh provocation test our patient did not

  2019-04-16

  

  During the ACh provocation test, our patient did not complain of chest pain, ECG showed no discernible ST-T changes, and CAG demonstrated no spastic findings. These indicate that ACh evoked the J wave by its direct pharmacological actions in this case. J waves are currently recognized as a surface E

• Worldwide there are an estimated specialist surgeons IQR ana

  2019-04-16

  

  Worldwide, there are an estimated 1 112 727 specialist surgeons (IQR 1 059 158–1 177 912), 550 134 anaesthesiologists (529 008–572 916) and 483 357 obstetricians (456 093–517 638; ). Low-income and lower-middle-income countries, representing 48% of the global population, have 20% of this workforce,

• Con frecuencia el tratamiento de

  2019-04-16

  

  Con frecuencia el tratamiento de la hippo pathway en Indias no es muy diferente; el bestiario que pudiera emerger de las crónicas abarca una fauna en la que la mirada acentúa lo diferente y lo exótico, el mito y la leyenda, pero ante todo se expresa y plasma en una estética en la que van juntos el

• El ansia renovadora que suscita tambi

  2019-04-16

  

  El ansia renovadora que suscita también se crea y re-crea en los paratextos ilustrados, que en cierto modo también sugieren una performatividad discursiva aplicada a la realidad convulsa de México en la revista Futuro, que puede observarse en la imagen y que se ha titulado, “Defensores del orden”.

• br Role of the funding source br Contributions br

  2019-04-15

  

  Role of the funding source Contributions Conflicts of interest Acknowledgments The authors would like to thank the patients who participated in this study and their families. The authors would also like to acknowledge the writing assistance of Stephen Mosley, Ph.D., of Knowledge Point 36

• Rabies has no cure and by the time of clinical

  2019-04-15

  

  Rabies has no cure, and by the time of clinical onset it is invariably fatal. More than 95% of deaths occur in Africa and Asia, 80% of which are in people living in rural, underserved populations, most of whom are children. Community awareness about the power of preventing dog bites and of life-savi

• In our survey the mean DEFS DMFS index was

  2019-04-15

  

  In our survey, the mean DEFS/DMFS index was higher for the  6-years-old group (17.18). During early development, younger children often have difficulty carrying out proper oral care due to their physical limitations. After 6 years of age, the exfoliation of primary teeth and the eruption of permanen

• br Conclusions br Conflict of

  2019-04-15

  

  Conclusions Conflict of interest Introduction Gastrointestinal stromal tumor (GIST) arises from the mesenchymal tissue of the gastrointestinal tract. The annual incidence of this condition is 7 cases per million people in the West. However, the incidence could in fact be higher in Asian pop

• As shown in Fig out

  2019-04-15

  

  As shown in Fig. 2, 40 out of the 60 patients (66.6%) who developed amiodarone-induced hypothyroidism, and 10 out of the 30 patients (33.3%) who developed amiodarone-induced hyperthyroidism, were diagnosed within two years of Asiatic acid of amiodarone therapy. Amiodarone-induced hypothyroidism dev

• In MM the optimal sequence or combination of

  2019-04-15

  

  In MM, the optimal sequence or combination of the different therapeutic regimens available remains unclear and information is needed on the efficacy of each treatment after various prior therapies. Although a substantial number of different regimens and schedules were used for the treatment of first

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