• Paraguay es puntual en la redacci n del

  2019-06-28

  

  Paraguay es puntual en la redacción del Artículo 8 de su Constitución Nacional cuando dice que “Las actividades susceptibles de producir alteración ambiental serán reguladas por la ley. Asimismo, ésta podrá restringir o prohibir aquéllas que califique peligrosas”. Describe allí las actividades que p

• Tal como lo expresan los cantos rituales registrados por Ech

  2019-06-28

  

  Tal como lo expresan los cantos rituales registrados por Echeverri, las alusiones Omecamtiv mecarbil la orfandad siempre están asociadas con la curación social e histórica que se consigue mediante el trabajo agrícola y el yetárafue, la conducta adecuada. Echeverri articula este análisis de la tradic

• br Materials and methods br Results br

  2019-06-28

  

  Materials and methods Results Discussion In recent years, it has been revealed that miRNAs are critical members of complex regulatory systems. SNPs or mutations occurring in the miRNA gene region may disturb the properties of miRNAs and result in defect in protein translation of target mRNA

• Our group then carried out

  2019-06-28

  

  Our group then carried out a study to determine the substrate sites and arrhythmogenic mechanisms of the BrS [29]. We found that all our BrS patients had abnormal low voltage, fractionated late potentials exclusively clustering in the anterior aspect of the RVOT epicardium and not seen anywhere else

• In the current era nearly all cases

  2019-06-28

  

  In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud

• To overcome these resistance mechanisms in

  2019-06-28

  

  To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro

• br We value the efforts

  2019-06-28

  

  We value the efforts of Akram Ahmad and colleagues (August, 2016) in highlighting an important issue related to the regulation of antibiotic fixed-dose combination drugs (FDCs) in India. Moreover, we agree with Ahmad and colleagues that actions taken by the Indian Government to ban irrational FDCs

• Lymphocytic infiltrates in thyroid cancer may suggest

  2019-06-28

  

  Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod

• br Mechanisms of arrhythmias Several schemes have

  2019-06-28

  

  Mechanisms of arrhythmias Several schemes have been used to classify the mechanisms of cardiac arrhythmias. Traditionally, these have been divided into nonreentrant and reentrant activity [11]. An alternative scheme divided them into those occurring at the cellular and tissue levels [12]. A dynam

• This Ca overload activates the forward mode of

  2019-06-28

  

  This Ca2+ overload activates the forward mode of the Na+/Ca+ exchanger (NCX), increases the transient inward current (Iti), and induces ventricular arrhythmias due to delayed after depolarizations (DADs). Subtypes of CPVT Several subtypes of CPVT have been reported (Table 1). The most common typ

• br Discussion Pericardial adhesions often develop after open

  2019-06-28

  

  Discussion Pericardial adhesions often develop after open SMIP004 of surgery, rendering a percutaneous subxiphoidal pericardial approach challenging [1–5]. Such adhesions are anticipated to be less dense in the inferior wall than in the anterior wall of the LV [1]. Therefore, there may be a chan

• The strategy seeks to reduce preventable mortality This

  2019-06-28

  

  The 25×25 strategy seeks to reduce preventable mortality. This emphasis leads to the selection of the four disorders specified in the strategy (cardiovascular disease, diabetes, cancer, and chronic respiratory disease), which account for 87% of all deaths from NCDs (). However, when the burden of di

• br In their Comment on the use of

  2019-06-28

  

  In their Comment on the use of antenatal corticosteroids to reduce preterm infant deaths, Kishwar Azad and Anthony Costello advise “extreme caution” before scale-up in low-income settings. They emphasise maternal sepsis as a concern but cite only one trial in which dexamethasone resulted in a sign

• However days after he completed the last

  2019-06-27

  

  However, 10 days after he completed the last chemotherapy round with etoposide, the patient again visited our emergency department manifesting a fever. Lab data reported leukopenia, anemia, and elevated LDH (leukocyte:3600/μL, hemoglobin:10.9 g/dL, platelet:168 × 103/μL, and LDH:498 U/L). Thereafter

• br Therapy for the CPVT br Conflict

  2019-06-27

  

  Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele

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