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br Discussion The use of carp primary cell
2020-09-05

Discussion The use of carp primary cell cultures proved to be a valuable approach to evaluate the piscine immune response. A. hydrophila was a more potent stimulator of NO formation by carp leukocytes compared to commercial LPS often used for leukocyte stimulation (Mustafa and Olson, 1998, Chao e
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br Acknowledgments br Introduction Inflammation is the prote
2020-09-05

Acknowledgments Introduction Inflammation is the protective reaction of the body to infection, injury, or irritation with the aim to remove harmful stimuli such as pathogens, damaged cells, or allergic irritants and to initiate the healing process. Inflammatory abnormalities play a crucial rol
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Consistent with a clear separation of biological function be
2020-09-05

Consistent with a clear separation of biological function between ARISC and BRISC in cells, mutations in BRCC36 and Abraxas are prevalent in cancer genomes whereas mutations in KIAA0157 are rare. A survey of the Catalogue of Somatic Mutations in Cancer (COSMIC) consortium, revealed that to date, 37
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Eptifibatide sale br Conclusion br Conflict of
2020-09-05

Conclusion Conflict of interest Author contributions Acknowledgements Piyamas Kanokwongnuwut was supported by the Development and Promotion of Science and Technology Talent Project (DPST), Royal Thai Government Scholarship. Funding for the work was provided by the Attorney General’s Depa
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br Materials and methods br Results The monoclonal antibody
2020-09-05

Materials and methods Results The monoclonal antibody (mAb), 12G5, reacts specifically with the human fusin protein and recognizes the protein on many T-cell lines such as the SUP-T1 Ginsenoside Rd receptor (Endres et al., 1996). As shown in Fig. 1, AMD3100 at 25 μg/ml completely inhibited th
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This study evaluated the role
2020-09-05

This study evaluated the role of SERT in classical fear conditioning using a SERT knockout rat model. We found a clear disruption of cue-conditioned fear in SERT−/− rats, as measured with the fear-potentiated startle. This disruption was due to a deficit in fear acquisition and was accompanied by de
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br Disclosures br Introduction The presence of
2020-09-04

Disclosures Introduction The presence of anti-viral T-cell immunity is crucial for effective and sustained protection against Cytomegalovirus (CMV) following allogeneic stem cell transplantation (alloSCT) [1]. In vitro and in vivo T-cell depletion (TCD) via addition of the anti-CD52 monoclonal
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The purpose of this study is
2020-09-04

The purpose of this study is to investigate KDM1B expression and its functional significance in PC. We used lentivirus-mediated shRNA to down-regulate KDM1B expression in PC cell lines in vitro and detected the changes of cell proliferation and apoptosis. These studies provided a novel insight into
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HCV has evolved mechanisms to evade
2020-09-04

HCV has evolved mechanisms to evade humoral immune responses including high functional flexibility and variability of immunogenic portions of its envelope proteins. The highest sequence variability occurs in the first 27 death associated protein kinase of the N-terminus of E2, which is referred to
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In the SUMOylation pathway SCE as an
2020-09-04

In the SUMOylation pathway, SCE1 as an E2 enzyme has an important role in mediating the conjugation of SUMO to target proteins. The accumulated SUMO conjugates in plants are associated with abiotic stress responses (Castro et al, 2012). We performed a drought stress analysis on WT plants, induced by
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It is reported that sympathetic nerve activity is
2020-09-04

It is reported that sympathetic nerve activity is increased in the SHR strain compared with that in the WKY strain (Judy and Farrell, 1979, Lundin et al., 1984, Sugimura et al., 2008) and NA content is increased in the CB of the New Zealand strain of hypertensive rat compared with that in normotensi
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Aripiprazole br Phenotypic responses alkylation induced cell
2020-09-04

Phenotypic responses: alkylation-induced cell death and mutagenesis E. coli alkB mutants were isolated in a screen for strains specifically sensitive to the cytotoxicity of MMS but not UV-irradiation. This was the first indication that the AlkB protein is a primary cellular defence against alkyla
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br Materials and methods br Results br
2020-09-04

Materials and methods Results Discussion EP is an important tick borne disease caused by T. equi and B. caballi. Current chemotherapeutic drugs for EP are limited, as only diminazene aceturate and imidazole dipropionate are available. Novel and effective chemotherapeutics for treatment of E
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Fostamatinib As part of a program to explore the key binding
2020-09-04

As part of a program to explore the key binding interactions between the core of 1 and DGAT-1 a systematic analysis of the aminopyrimidine subunit was initiated. A potential approach to improving passive permeability within this series would be to increase lipophilicity via incorporation of substitu
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br Materials and methods br
2020-09-04

Materials and methods Results and discussion Conclusions Clitocypin is another member of the mycocypin family of cysteine protease inhibitors that is unique to gbr properties receptor shown to exhibit strong insecticidal activity against Colorado potato beetle larvae. This effect is concen
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