• br Conclusion br Ethics statements file br Conflict

  2022-09-09

  

  Conclusion Ethics statements file Conflict of interest Acknowledgements This study was supported by the National Research Foundation of Korea (NRF) Grant funded by the Korean Government (MSIP) (Nos. 2011-0030074 and 2018R1D1A3B07050361) and Sookmyung Women’s University Specialization Pro

• One major mode of bioelectric action

  2022-09-09

  

  (2) One major mode of bioelectric action is that of an amplifier of subcellular symmetry-breaking mechanisms into tissue-wide order. An example is the patterning of the embryonic left (L)-right (R) axis reviewed in References [57, 58]; the following scheme describes the data obtained largely from th

• br STAR Methods br Introduction Secretase is a membrane embe

  2022-09-09

  

  STAR★Methods Introduction γ-Secretase is a membrane-embedded proteolytic complex belonging to a diverse family of intramembrane-cleaving proteases and is composed of four integral membrane proteins: presenilin (PS), nicastrin (NCT), anterior pharynx-defective 1 (Aph-1), and presenilin enhancer

• Of the cases identified herein three

  2022-09-09

  

  Of the 52 cases identified herein, three known and 11 novel FGFR fusion partners were identified. Notably, an oligomerization domain, including coiled-coil dimerization domains similar to that seen in echinoderm microtubule associated protein like 4 gene (EML4), which is the most common ALK partner

• The replenishment time course of

  2022-09-08

  

  The replenishment time course of already-tethered vesicle to became release ready, was examined by TIRFM imaging combined with calcium uncaging. By UV-flash photolysis of caged calcium, intracellular calcium concentration raises rapidly and homogenously throughout the cell (Ellis-Davies, 2008). Upon

• ekb-569 In conclusion the present study shows that the endot

  2022-09-08

  

  In conclusion, the present study shows that the endothelin system is of importance in the cardiopulmonary vascular pathophysiology of porcine endotoxin shock. In this model, combination of a selective endothelin ETA and a selective endothelin ETB receptor antagonist markedly improved pulmonary circu

• The hyperacetylation of histone proteins by HATs is

  2022-09-08

  

  The hyperacetylation of histone proteins by HATs is known to be associated with gene activation [51]. In particular, p300, which is a transcription factor having HAT activity, links activators to the transcription machinery at promoters [52]. The p300/CBP complex dynamically regulates hundreds of di

• In conclusion the most salient

  2022-09-08

  

  In conclusion, the most salient observation from this study was that PAE reduced the expression of HDC protein expression in dentate gyrus, cerebral cortex, and cerebellum, but not in the caudate nucleus or ventral hypothalamus. The regional basis for this heightened sensitivity is not known, but it

• br Materials and methods br Results br Discussion Both EMT

  2022-09-08

  

  Materials and methods Results Discussion Both EMT of the tubular epithelial Vialinin A and the activation of fibroblasts are critical factors in the pathogenesis and progression of renal interstitial fibrosis. Accumulating evidence implicates EMT in the onset and pathogenesis of renal inte

• The balance and composition of the

  2022-09-08

  

  The balance and composition of the gut microflora can be altered by the use of antibiotics or by colonization of the intestine by pathogens. This change may also induce, or be induced by, modifications in the body’s immune response, ultimately leading to disease. Thus, when intestinal homeostasis is

• Recent evidence suggests that HCA can also mediate antineuro

  2022-09-08

  

  Recent evidence suggests that HCA2 can also mediate antineuroinflammatory effects [63]. Studies in this field were initiated when monomethyl fumarate, the metabolite of DMF, was shown to be an agonist of HCA2[5]. DMF at the same time was shown to not only have beneficial effects in the treatment of

• Several studies have found that GPR possesses

  2022-09-08

  

  Several studies have found that GPR55 possesses a distinct pharmacology from that of CB1 and CB2, and that only certain cannabinoids act at this receptor. In transfected Estradiol synthesis expressing hGPR55, out of more than 20 synthetic and endogenous cannabinoids evaluated, only 2 compounds, SR1

• The mechanisms of action of MMF

  2022-09-08

  

  The mechanisms of action of MMF and DMF are not well understood, but a growing body of evidence has demonstrated that DMF may act on both the neurodegenerative and inflammatory response of MS patients. The majority of the data related to the mechanism of action of DMF/MMF demonstrates the associatio

• Originally identified as a GPCR upregulated on Burkitt lymph

  2022-09-08

  

  Originally identified as a GPCR upregulated on Burkitt lymphoma cells upon Epstein-Barr virus infection (Birkenbach et al., 1993), Ebi2 was later found to play critical roles in immunity by regulating the migration of activated NKY 80 australia to extrafollicular sites for early plasmablast response

• Our results on the association of selenium deficiency and vi

  2022-09-08

  

  Our results on the association of selenium deficiency and vitamin A deficiency being associated with greater CD4 recovery during treatment were surprising. As we had hypothesized a relationship in the opposite direction (deficiency being associated with lower CD4 recovery), we can only reflect on po

15510 records 366/1034 page Previous Next First page 上5页 366367368369370 下5页 Last page