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mRNA transcription kit The initial demonstration of the pote
2024-12-27

The initial demonstration of the potential of MALDI-TOF MS for testing antifungal susceptibility of pathogenic fungi came from a proof-of-concept study by Marinach et al. [31] who monitored the changes of the proteome of C. albicans mRNA transcription kit exposed to different concentrations of fluco
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In conclusion there are only a few experimental
2024-12-27

In conclusion, there are only a few experimental reports evaluating the influence of Adrenomedullin fragment on allergy. With the exception of studies using macrolides, most point to their harmful effect on the severity of this disease. Future studies will be crucial to define the impact of antibio
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For the derivatives a c another likely explanation for antif
2024-12-27

For the derivatives 3a–3c, another likely explanation for antifungal properties is that polymers bearing primary amine groups and secondary phosphoryl groups formed, enhancing complexation with the phosphate groups, and the complexes are amphiphilic (Palermo, Lee, Ramamoorthy, & Kuroda, 2011). The a
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cell division cycle br Materials and methods br Results and
2024-12-27

Materials and methods Results and discussion Conclusions Acknowledgements Introduction Infections in children aged 0–21 years who reside in long-term care (LTC) facilities are common due to underlying complex medical conditions, use of invasive devices such as urinary catheters and ve
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DNA recombination enzyme Various antiangiogenic drugs have b
2024-12-27

Various antiangiogenic drugs have been analyzed over the last few years; noteworthy, bevacizumab, a monoclonal antibody against VEGF-A, alone or in combination with cytotoxic agents showed interesting results in terms of radiographic response rates and progression-free survival in initial phase 2 st
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br Role of AR in models of neointima formation
2024-12-27

Role of AR in models of neointima formation Investigations into the pathogenesis of lesion formation have often used acute models of mechanical damage to assess the mechanisms regulating the fibro-proliferative response to arterial injury. Models of acute injury used for this purpose include: lig
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Introduction Inflammasomes are large cytosolic
2024-12-27

Introduction Inflammasomes are large cytosolic protein complexes with multiple components that trigger a rapid immune response against pathogen-associated molecular pattern UO 126 (PAMPs) during pathogen infections or damage-associated molecular pattern molecules (DAMPs) during tissue damage [1].
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br Introduction The chronic inflammation is one of the
2024-12-26

Introduction The chronic inflammation is one of the leading events involved in the aetiology of many chronic-degenerative diseases including diabetes, atherosclerosis, arthritis and cancer (Coussens and Werb, 2002). Monocytes/macrophages lineage plays an important role during inflammation through
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Recently biosensors based on enzyme mimicking organic inorga
2024-12-26

Recently, biosensors based on enzyme-mimicking organic-inorganic hybrid nanomaterials such as protein or DNA-Cu nanoflowers (Batule et al., 2015, Park et al., 2017), Fe-aminoclay (Lee et al., 2013), and MOFs (Ai et al., 2013, Dong et al., 2015, Feng et al., 2012, Liu et al., 2013, Qin et al., 2013,
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Although ACE genetic variance does not influence
2024-12-26

Although ACE genetic variance does not influence the level of bradykinin significantly, the bradykinin level tends to be affected by ACE inhibitor therapy used by patients. ACE inhibitor reduces the ACE activity that may lead to the accumulation of serum bradykinin. The level of bradykinin tends to
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NLX a k a F or befiradol exhibits
2024-12-26

NLX-112 (a.k.a. F13640 or befiradol), exhibits nanomolar affinity at 5-HT1A receptors, and, in fluvastatin side effects to the 5-HT1A receptor agonists listed above, it presents exceptional selectivity and high efficacy at these receptors (Colpaert et al., 2002, Newman-Tancredi et al., 2017). Addit
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br Acknowledgement This work was funded by NIH NINDS
2024-12-26

Acknowledgement This work was funded by NIH/NINDS grant number NS080967 to C. Waites. Introduction Macro-autophagy also called autophagy is a conserved pathway for the lysosomal degradation and recycling of intracellular materials. It is instrumental for the homeostasis of cells and tissues a
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Introduction The MMR system keeps the
2024-12-26

Introduction The MMR system keeps the fidelity of replication by repairing replication errors such as base-base mispairs and insertions/deletions. It plays a substantial role in restoring the fidelity of DNA and contributing to genome integrity [1]. The components of MMR are conserved in a broad r
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br Acknowledgments br Introduction Human innate
2024-12-26

Acknowledgments Introduction Human innate immune system provides first line of defense against multiple viral or bacterial attacks, and provides critical surveillance against oncogenic development. Evidences show that individuals with primary immunodeficiency or induced immunosuppression durin
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Findings of the present study
2024-12-26

Findings of the present study provide a molecular mechanism for the elevated ASK1 expression in obesity and how it may be functionally linked to whole-body insulin resistance. The role our findings assign to increased E2F1 in upregulating ASK1 parallels the capacity of this transcription factor to r
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