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Introduction An association of elevated
2024-02-21
Introduction An association of elevated branched-chain 1 98 (BCAA—Leu, Val, Ile) with obesity and insulin resistance was first reported nearly 50 years ago (Felig et al., 1969). With the advent of metabolomics technologies, it has since become apparent that the association of BCAA and related meta
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Furthermore different s http www apexbt com media diy
2024-02-21
Furthermore, different studies have described the APP as useful biomarkers in monitoring the post-ovariohysterectomy period in bitches with pyometra [12,14,52,53], similar to what was observed in queens in the present study. In our study, significant decreases in concentrations of a major (SAA) and
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Introduction Antimicrobial resistance is a growing health th
2024-02-21
Introduction Antimicrobial resistance is a growing health threat worldwide that has been associated with incorrect prescription and overuse of MPI-0479605 [1]. Considering that physicians play a central role in antibiotic usage, a better understanding of their prescribing behaviours and their know
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Human testicular peritubular cells HTPCs are also the
2024-02-20
Human testicular peritubular MS436 (HTPCs) are also the only human testicular cell type that can be isolated, cultured and studied in vitro (Albrecht et al., 2006, Mayerhofer, 2013). Results from recent studies indicate that their roles go beyond sperm transport and include immunological functions.
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IMR-1 To date the modes of actions of
2024-02-20
To date, the modes of actions of pharmaceuticals in humans and mammals are well-known (Fent et al., 2006), whereas knowledge of aquatic organisms, particularly invertebrates, is limited. This is problematic as these contaminants/pollutants have potentially harmful effects on wildlife organisms that
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The structures of these compounds were confirmed from their
2024-02-20
The structures of these compounds were confirmed from their spectral and micro analytical data. Based on [M + H] 367, molecular formula of was established as CHON. The IR spectrum of showed Nitrocefin due to CO stretching at 1700 Cm & OH stretching at 3188 Cm indicating that compound contains one
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br Conclusion br Conflicts of interest br Introduction RNA
2024-02-20
Conclusion Conflicts of interest Introduction RNA interference is a specific post-transcriptional gene silencing mechanism within a cell via the transfection of microRNAs (miRNA), exogenous small interfering RNAs (siRNA) or small hairpin RNAs (shRNA) [1–3]. Transfection of shRNA can be done
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Prostate cancer is the second leading cause of cancer relate
2024-02-20
Prostate cancer is the second leading cause of cancer-related death in men in the United States [25]. Similar to pancreatic cancer, prostate cancer has few diagnostic options available, particularly to differentiate indolent from aggressive disease. Axl is also overexpressed in ∼50% of prostate canc
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In order to further explore whether the cytoprotective effec
2024-02-20
In order to further explore whether the cytoprotective effect of isogarcinol against oxidative stress in H2O2-induced HepG2 Oxytocin is a consequence of the breakdown of the endogenous antioxidant defence mechanism, we measured the LDH release, MDA levels, GSH levels and SOD activity. A large body
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Additional support for a role
2024-02-20
Additional support for a role of HMGN1 in enhancing DNA repair comes from studies of transcription-coupled repair (TCR) in human cells. Lesions in the template strand of DNA induced by UV light stall the movement of RNA polymerase II (RNAPII) and interrupt transcription. Removal of these transcripti
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br Obstructing SNARE zippering Sharma et al
2024-02-19
Obstructing SNARE “zippering” Sharma et al. demonstrated for the first time that in the postmortem AD brains, the level of SNARE complex formation, which is necessary for driving synaptic vesicle fusion at the presynaptic active zone, is significantly reduced [123]. In the absence of changes in e
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Inflammatory factors released by activated cells
2024-02-19
Inflammatory factors released by activated cells during AD are very important for the disease progression. Not only several inflammatory cytokines, such as IL-1β, IL-18, and IL-33, but also anti-inflammatory ones, as IL-10 and IL-13, are upregulated in the brain of AD patients (Morimoto et al., 2011
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Salvia the largest genus in the family Lamiaceae comprises
2024-02-19
Salvia, the largest genus in the family Lamiaceae, comprises over 900 species that are distributed globally [14], [15], [16]. The genus Salvia has been assessed in many studies because it is a rich source of polyphenol compounds, of which more than 160 have been isolated from plants in the genus, so
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ppar agonist Mass spectrometry MS analysis and selective enr
2024-02-19
Mass spectrometry (MS) analysis and selective enrichment methods of phosphorylated proteins are powerful tools that can help address these challenges. Recent advances in MS have made it possible to analyze signaling pathways by facilitating high-throughput identification of phosphorylation sites wit
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br Conclusions Triptans are HT B D
2024-02-19
Conclusions Triptans are 5-HT1B/1D/(1F) receptors agonists and are considered as the gold standard for acute migraine treatment that have been proven effective. Unfortunately, they are contraindicated in patients with cardiovascular diseases due to their vasoconstrictor (side) effects (MaassenVan
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